Revelation 14:8

⁸ Then another angel, a second, followed, saying, “Fallen, fallen is Babylon the great! She has made all nations drink of the wine of the wrath of her fornication.”

The writer at bibleref.com explains Babylon the Great as being the representation of the worship of satanic principles such as lust and greed, and this article at Frontline gives a good synopsis of Revelation with a lot of historical background, and comes to the conclusion, like many scholars, that Babylon the Great/the Whore of Babylon signifies the Roman Empire. 

Revelation 18

 18 After this I saw another angel coming down from heaven, having great authority; and the earth was made bright with his splendor. ² He called out with a mighty voice,

“Fallen, fallen is Babylon the great!
    It has become a dwelling place of demons,
a haunt of every foul spirit,
    a haunt of every foul bird,
    a haunt of every foul and hateful beast.
³ For all the nations have drunk
    of the wine of the wrath of her fornication,
and the kings of the earth have committed fornication with her,
    and the merchants of the earth have grown rich from the power of her luxury.”